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Effect of Adrenal Estrogens on the Growth of Dimethylbenz(A)anthracene-Induced Mammary Carcinoma in the Rat

โœ Scribed by Sophie Dauvois; Fernand Labrie

Book ID
119864896
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
154 KB
Volume
595
Category
Article
ISSN
0890-6564

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โœ Shouqi Luo; Milos Stojanovic; Claude Labrie; Fernand Labrie ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 153 KB ๐Ÿ‘ 3 views

The novel anti-estrogen EM-800 and medroxyprogesterone acetate (MPA) inhibit estrone (E 1 )-stimulated growth of dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in a rat model. After 65 days, ovariectomy (OVX) decreased total tumor area to 9.6 ุŽ 3.9% of initial size, while E 1 (1.0 ยตg, s.c.,