𝔖 Bobbio Scriptorium
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Effect of additives on hydroxypropyl methylcellulose gel structure and controlled release properties

✍ Scribed by J.S. Smith; T.F. Dolan; R.J. Macrae

Book ID
117628928
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
154 KB
Volume
4
Category
Article
ISSN
0928-0987

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From a mixture of a methanol solution of ibuprofen (IB) and an aqueous solution of hydroxypropyl methylcellulose (HPMC), clear, uniform sol was obtained at the methanol/water proportion 7/3. When sol was brought to dryness, nanocomposite gel was obtained with amorphous IB particles of 20-50 nm dispe