Effect of Adding an Amphiphilic Solubilization Improver, Sucrose Distearate, on the Solubilization Capacity of Nonionic Microemulsions
✍ Scribed by Kenji Aramaki; Tomohiro Hayashi; Toshiya Katsuragi; Masahiko Ishitobi; Hironobu Kunieda
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 97 KB
- Volume
- 236
- Category
- Article
- ISSN
- 0021-9797
No coin nor oath required. For personal study only.
✦ Synopsis
We have studied the effect of adding sucrose distearate (2C(18)SE) on the solubilization capacity of microemulsions formed in the water/C(12)EO(6)/n-decane system. Upon addition of 2C(18)SE to the binary water/C(12)EO(6) system, a lamellar liquid crystal region developed. This suggests that the rigidity of the surfactant layer is strengthened. The solubilization of water and n-decane in the bicontinuous microemulsions increases about three times upon replacing 10% C(12)EO(6) with 2C(18)SE; besides, the HLB temperature is not greatly affected by 2C(18)SE. On the other hand, sucrose monostearate (C(18)SE) does not have such a function. The effect of added 2C(18)SE on the solubilization capacity of the discrete droplet-type o/w or w/o microemulsions was also studied. The efficiency of the solubilization-improving effect is reduced when the system is far from the HLB temperature. Copyright 2001 Academic Press.