It was reported that the mean value of the extent of absolute oral bioavailability (F) of oltipraz at a dose of 20 mg/kg was 41.2% and only 2.68% of the oral dose was unabsorbed from the gastrointestinal tract in rats. Hence, the low F in rats could be due to considerable first-pass (gastric, intest
โฆ LIBER โฆ
Effect of acute hepatic failure on the hepatic first-pass effect of 5-fluorouracil in rats
โ Scribed by Masashi Nagata; Yumi Hidaka; Muneaki Hidaka; Yohei Kawano; Tomomi Iwakiri; Manabu Okumura; Kazuhiko Arimori
- Book ID
- 111771102
- Publisher
- Pharmaceutical Press
- Year
- 2010
- Tongue
- English
- Weight
- 138 KB
- Volume
- 62
- Category
- Article
- ISSN
- 2042-7158
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