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Effect of acetylcholinesterase inhibitors on AChE-Induced PrP106–126 aggregation

✍ Scribed by M. V. Clos; M. Pera; M. Ratia; S. Román; P. Camps; D. Muñoz-Torrero; L. Colombo; M. Salmona; A. Badia


Book ID
111640024
Publisher
Humana Press Inc
Year
2006
Tongue
English
Weight
68 KB
Volume
30
Category
Article
ISSN
0895-8696

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## Abstract The prion protein peptide PrP106‐126 induces cell apoptosis through mechanisms involving production of intracellular reactive oxygen species. The present study investigated the effects of edaravone, a potent free radical scavenger in clinical use, on cell cytotoxicity induced by PrP106‐