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Effect of Acetylcholine on Mortality of Mice from Sepsis and Proinflammatory Cytokine Production

✍ Scribed by P. F. Zabrodskii


Publisher
Springer US
Year
2011
Tongue
English
Weight
385 KB
Volume
150
Category
Article
ISSN
0007-4888

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Tetomilast suppressed production of proi
✍ Hitoshi Ichikawa; Susumu Okamoto; Nobuhiko Kamada; Hisashi Nagamoto; Mina T. Kit πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 374 KB

## Background: Tetomilast (opc-6535) was originally developed as a compound inhibiting superoxide production in neutrophils. although its mechanism of action is not completely understood, phosphodiesterase type 4 inhibitory function has been postulated. the therapeutic effect of pde4 inhibitors has