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Effect of acetaminophen on hepatic content and biliary efflux of glutathione disulfide in mice

✍ Scribed by Charles V. Smith; Hartmut Jaeschke

Book ID
113137207
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
466 KB
Volume
70
Category
Article
ISSN
0009-2797

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Acetaminophen (APAP) with or without ascorbyl stearate (AS) or ascorbyl palmitate (AP) was administered by gavage to male Swiss-Webster mice at a dose of 600 mg/kg for each chemical. The biochemical markers of hepatotoxicity, serum transaminases (serum glutamate pyruvate transaminase [SGPT], serum g