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Effect of a single amino acid substitution on stability of conformation of a protein

✍ Scribed by YUTANI, KATSUHIDE; OGASAHARA, KYOKO; SUGINO, YOSHINOBU; MATSUSHIRO, AIZO


Book ID
109704891
Publisher
Nature Publishing Group
Year
1977
Tongue
English
Weight
243 KB
Volume
267
Category
Article
ISSN
0028-0836

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## Abstract The adiabatic compressibility (Ξ²~__s__~) was determined, by means of the precise sound velocity and density measurements, for a series of single amino acid substituted mutant enzymes of __Escherichia coli__ dihydrofolate reductase (DHFR) and aspartate aminotransferase (AspAT). Interesti