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Effect of 5-fluorouracil on methotrexate transport and cytotoxicity in HT29 colon adenocarcinoma cells

✍ Scribed by Chen, Marianne F.; Chen, Li T.; Boyce, H.Worth


Book ID
122623697
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
736 KB
Volume
88
Category
Article
ISSN
0304-3835

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Adaptation of HT-29 cells to increasing concentrations of methotrexate (MTX) results in the selection of differentiated populations which show sequential dose-dependent changes of their differentiated phenotype with, at the highest concentrations (0.1 and 1 mM), a shift of differentiation from a muc