Effect of 5′-deoxy-5′-S-isobutyl-adenosine (siba) on mouse mammary tumour cells and on the expression of mouse mammary tumour virus
✍ Scribed by Catherine Terrioux; Michel Crépin; François Gros; Malka Robert-Géro; Edgar Lederer
- Book ID
- 118312640
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 336 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0006-291X
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The objective of this study was to determine if adenosine alters growth of mammary epithelium. Mouse mammary epithelial cells (NMuMG) were cultured in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 h, EGF (0-100 ng/ml) and/or adenosine (0-100 microM) was added. Adenosine
## Abstract Antibody levels to mouse mammary tumor virus (MuMTV) in sera of C3H/BI, C57BL/6 and AKR mice were assayed by an enzyme‐linked immunosorbent assay (ELISA). It was found that antibody levels to MuMTV were highest in sera of C3H/Bi females which have a high incidence of breast cancer and l