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Effect of 4,4-dideuteration of reduced nicotinamide-adenine dinucleotide phosphate on the mixed function oxidases of hepatic microsomes

โœ Scribed by Holtzman, Jordan L.

Book ID
126215545
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
731 KB
Volume
9
Category
Article
ISSN
0006-2960

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Reduced nicotinamide adenine dinucleotid
Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells
โœ Samuele De Minicis; Ekihiro Seki; Christoph Oesterreicher; Bernd Schnabl; Robert ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 900 KB

Although leptin induces fibrotic activity in hepatic stellate cells (HSCs), the mechanisms are not entirely understood. To investigate the potential role of reduced nicotinamide adenine dinucleotide phosphate oxidase (NADPH) and reactive oxygen species (ROS) in leptin signaling in HSCs, we analyzed