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Effect of 4-aminopyridine and verapamil on the inhibitory action of normorphine on the guinea-pig ileum

โœ Scribed by Ahmad Rezvani; J.Pablo Huidobro-Toro; E. Leong Way

Book ID
115877339
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
301 KB
Volume
86
Category
Article
ISSN
0014-2999

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Antagonistic effects of taurine and 4-aminopyridine on guinea pig ileum
โœ M. E. Arzate; H. Ponce; Herminia Pasantes-Morales ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 518 KB

The effects of 4-aminopyridine (4-AP) and of taurine on the guinea pig ileum were examined. Four-AP increases the basal activity from 1.3 to 6.45 cm2/min. This effect is atropine-sensitive and calcium-dependent. Taurine counteracts the effects of 4-AP on muscle contracture in a concentration-depende