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Effect of 3-Hydroxyproline Residues on Collagen Stability

✍ Scribed by Jenkins, Cara L.; Bretscher, Lynn E.; Guzei, Ilia A.; Raines, Ronald T.

Book ID
127157388
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
188 KB
Volume
125
Category
Article
ISSN
0002-7863

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πŸ“œ SIMILAR VOLUMES

O-acylation of hydroxyproline residues:
O-acylation of hydroxyproline residues: Effect on peptide-bond isomerization and collagen stability
✍ Cara L. Jenkins; Alexander I. McCloskey; Ilia A. Guzei; Eric S. Eberhardt; Ronal πŸ“‚ Article πŸ“… 2005 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 194 KB

## Abstract In collagen, strands of the sequence XaaYaaGly form a triple‐helical structure. The Yaa residue is often (2S,4__R__)‐4‐hydroxyproline (Hyp). The inductive effect of the hydroxyl group of Hyp residues greatly increases collagen stability. Here, electron withdrawal by the hydroxyl group i