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Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor on sterol absorption in hypercholesterolemic subjects

✍ Scribed by Fady J. Ntanios; Peter J.H. Jones; Jiri J. Frohlich


Book ID
117180722
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
634 KB
Volume
48
Category
Article
ISSN
1532-8600

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## Abstract Elevated 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase expression supports synthesis of prenyl pyrophosphate intermediates required for tumor growth. In this study, the copy number of HMG‐CoA reductase mRNA was determined in solid tumor and leukemic cell lines using competit