Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on anti-CD3-induced changes in T-cell subsets and cytokine production
β Scribed by R.A. Prell; J.A. Oughton; N.I. Kerkvliet
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 809 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The administration of single oral doses of 200 ΞΌg kg^β1^ of 2,3,7,8βtetrachlorodibenzoβ__p__βdioxin to females of the outbred, Lac: P strain of rat results in the formation of hepatic multinucleate cells by cell fusion. Liver cell plasma membranes isolated 6 or 11 days after dosing show
## Abstract Dioxin is suspected to cause adverse effects on the development of the central nervous system (CNS). To investigate the neurotoxic effects of dioxin on the differentiation of astrocytes, rat C6 glial cell line was used as a model, because these cells are induced to express astrocyte mar