Effect of 1,25-dihydroxy vitamin D3 on fracture healing and bone remodeling in ovariectomized rat femora
β Scribed by Lingjie Fu; Tingting Tang; Yanying Miao; Yongqiang Hao; Kerong Dai
- Book ID
- 116321468
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 559 KB
- Volume
- 44
- Category
- Article
- ISSN
- 8756-3282
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## Abstract To investigate the effect of 25βOHβvitamin D supplements (calcidiol) on fracture healing in the elderly, an experimental model with 15 18βmonthβold female Wistar rats was designed. An experimental fracture in the middle third of both femora of each rat was made. Then the rats were rando
To examine the effect of alendronate (4-amino-1-hydroxybutylidene bisphosphonate) on fracture repair, the drug was given to mature beagle dogs orogastrically at 2 mg/kg/day for 9 weeks preceding fracture. 16 weeks after fracture, or both before and after fracture (25 weeks). A transverse mid-diaphys