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EEG correlates of genetic heterogeneity in angelman and prader-willi syndromes: Evidence for deletion at 15q 11–13

✍ Scribed by Li Chen; Paul A. Hwang; Jeff S. Kobayashi; Ikuko Teshima; Roseanne Weksberg; Daune L. MacGregor


Book ID
119173406
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
129 KB
Volume
11
Category
Article
ISSN
0887-8994

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Deletion breakpoints associated with the
✍ Wendy P. Robinson; Roland Spiegel; Albert A. Schinzel 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 372 KB

Deletions of 15q11.2-q12 are associated with either the Prader-Willi (PWS) or Angelman (AS) syndromes. It has been suggested that excessive recombination in this region might explain the high frequency of such deletions, and the frequent involvement of chromosome 15 in translocations and nondisjunct