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EDRF release is a common pathway in the activation of guanylate cyclase by receptor agonists and calcium ionophores

✍ Scribed by Wanida S. Pou; Sovitj Pou; Gerald M. Rosen; Esam E. El-Fakahany


Book ID
115883194
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
142 KB
Volume
182
Category
Article
ISSN
0014-2999

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Vascular endothelial cells respond to a variety of physiological and pharrnacological stimuli by releasing free arachidonic acid from membrane phospholipids, thus initiating synthesis of prostacyclin. Previous work in our laboratory has demonstrated that the thrombin-stimulated deacylation is specif