✦ LIBER ✦
Edman-Abbau als analytische methode in der ‘Solid phase’-Peptidsynthese. Vorläufige Mitteilung
✍ Scribed by Peter Fankhauser; Peter Fries; Peter Stahala; Max Brenner
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- German
- Weight
- 442 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The systematic analysis of solid phase peptide synthesis by Edman degradation becomes possible by the development of a technique (high pressure liquid chromatography) for the determination of phenylthiohydantoins in trace amounts. By its qualitative beside the quantitative results the degradation method offers the possibility to follow formation and propagation of failure sequences over more than one synthetic cycle. Scope and limitations of the method are discussed.