𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Editorial: Peptide and peptidomimetic ligands of opioid receptors

✍ Scribed by Peter W. Schiller


Publisher
Wiley (John Wiley & Sons)
Year
1999
Tongue
English
Weight
22 KB
Volume
51
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


New opioid peptides, peptidomimetics, an
✍ C. T. Dooley; R. A. Houghten πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 132 KB πŸ‘ 1 views

Here we review the use of combinatorial libraries in opioid receptor assays. Following a brief description of the history of the combinatorial field, methods for the generation of synthetic libraries and the deconvolution of mixture-based libraries are presented. Case studies involving opioid assays

Complementarity of Ξ΄ opioid ligand pharm
✍ Henry I. Mosberg πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 426 KB

The elaboration of a pharmacophore model for the ␦ opioid receptor selective ligand JOM-13 (Tyr-c[D-Cys-Phe-D-Pen]OH) and the parallel, independent development of a structural model of the ␦ receptor are summarized. Although the backbone conformation of JOM-13's tripeptide cycle is well defined, con

Conformation–activity relationships of o
✍ Victor J. Hruby; Richard S. Agnes πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 141 KB πŸ‘ 1 views

The discovery of endogenous opioid peptides 25 years ago opened up a new chapter in efforts to understand the origins and control of pain, its relationships to other biological functions, including inflammatory and other immune responses, and the relationships of opioid peptides and their receptors

Structure and regulation of opioid recep
✍ Kirti Chaturvedi; Keith H. Christoffers; Kamalendra Singh; Richard D. Howells πŸ“‚ Article πŸ“… 2000 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 349 KB

Significant advances have been made in understanding the structure, function, and regulation of opioid receptors and endogenous opioid peptides since their discovery approximately 25 years ago. This review summarizes recent studies aimed at identifying key amino acids that confer ligand selectivity

Opioid peptide receptor studies, 11: Inv
✍ Heng Xu; Yi-Feng Lu; John S. Partilla; Qiao-Xi Zheng; Jia-Bei Wang; George A. Br πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 135 KB

Previous data obtained with the cloned rat Β΅ opioid receptor demonstrated that the ''super-potent'' opiates, ohmefentanyl (RTI-4614-4) and its four enantiomers, differ in binding affinity, potency, efficacy, and intrinsic efficacy. Molecular modeling (Tang et al., 1996) of fentanyl derivatives bindi