Editorial: Electrophoresis 17/2002

✍ Scribed by Ziad El Rassi

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 17 KB
• Volume: 23
• Category: Article
• ISSN: 0173-0835
• DOI: 10.1002/1522-2683(200209)23:17<2817::aid-elps2817>3.0.co;2-o

✦ Synopsis

For more than two decades, the large-scale or "global" study of proteins and the practice of two-dimensional (2-D) gel electrophoresis have been largely inseparable and interchangeable. The first use of the word "proteome" was in Electrophoresis (1995, 16,(1090)(1091)(1092)(1093)(1094)(1095) in an article by the group of Humphery-Smith. If the term "proteomics" had been coined 25 years ago, it would have been to better convey the capability to examine the complexity of the protein universe provided by 2-D gel electrophoresis. The pattern of protein spots provided by 2-D gels allowed for the first time what appeared to be a holistic view of the molecular level complexity of biological systems. For two decades papers on proteomics by 2-D gel electrophoresis were largely published in Electrophoresis.