Editorial: Cholesterol lowering spreads — a healthy future?

DMP 504, a novel hydrogel bile acid sequ

DMP 504, a novel hydrogel bile acid sequestrant: III. Safety, tolerability, and cholesterol-lowering in healthy hypercholesterolemic subjects

✍ James W. Hainer; Donald B. Hunninghake; Irma H. Benedek; Francis E. Broyles; Den 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB

This multiple-dose study of DMP 504, a hydrogel bile acid sequestrant, employed a randomized, double-blind, sequential-cohort design with placebo (blinded) and open-label cholestyramine (CS) controls. Ninety-three healthy primary hypercholesterolemic subjects (serum LDL cholesterol 130 to 200 mg/dL;