Editing of 31P NMR spectra of heart in vivo
β Scribed by Kevin M Brindle; Bheeshma Rajagopalan; Nicholas M Bolas; George K Radda
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 586 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-2364
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π SIMILAR VOLUMES
The magnetic field-dependent phosphodiester (PDE) signal found in "P NMR spectra of liver and brain has been studied using saturation transfer and proton decoupling techniques. This PDE component, which accounts for as much as 45% of the signal in vivo, has been identified as primarily phospholipid
6154) that edit into two subspectra according to the number of protons attached to 13 C nuclei being odd or even are introduced. These sequences can be useful for resolving spectral overlap, which is demonstrated on the molecule prednisolone [(11 b)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione].
Although the measurement of the pH of biological systems using the 31P NMR response of inorganic phosphate is well known, sometimes in blood absolute determination of the intensity and position of the Pi resonance is precluded by overlap from the doublet resonance of 2,3-diphosphoglycerate. Three te