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Ectopic WHN expression in transgenic mice causes developmental defects and epidermal hyperplasia

✍ Scribed by Prowse, David; Lee, David; Magro, Cynthia; Baden, Howard; Brissette, Janice


Book ID
119561919
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
204 KB
Volume
16
Category
Article
ISSN
0923-1811

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## Abstract Over‐expression of human FGF‐2 cDNA linked to the phosphoglycerate kinase promoter in transgenic (TgFGF2) mice resulted in a dwarf mouse with premature closure of the growth plate and shortening of bone length. This study was designed to further characterize bone structure and remodelin