✦ LIBER ✦

Ectopic production of prostate specific antigen by a breast tumor metastatic to the ovary

✍ Scribed by H. Yu; Dr. E. P. Diamandis; M. Levesque; P. Sismondi; P. Zola; D. Katsaros

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 266 KB
Volume: 8
Category: Article
ISSN: 0887-8013
DOI: 10.1002/jcla.1860080412

No coin nor oath required. For personal study only.

✦ Synopsis

We have recently reported that about 30% of breast tumors produce prostate specific antigen (PSA). We examined here, 99 primary ovarian cancer tumors and found relatively low levels of PSA in only three tumors. One patient with metastatic ovarian cancer from a primary breast tumor, produced relatively high levels of PSA and responded well to antiestrogen treatment although she was steroid receptor-negative. Another patient with metastatic ovarian cancer from a primary breast tumor did not produce PSA and did not respond to treatment although she was steroid hormone receptor-positive. This data describe for the first time, ectopic PSA production by a breast tumor at the ovarian metastatic site and further support the view that PSA is a favourable prognostic indicator in breast cancer. o 1994 Wiley-Liss, Inc.

📜 SIMILAR VOLUMES

Prostate-specific antigen: Monitoring th

Prostate-specific antigen: Monitoring the response of carcinoma of the prostate to radiotherapy with a new tumor marker

✍ George S. Dundas; Arthur T. Porter; Peter M. Venner 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 393 KB 👁 2 views

Serum mucin antigens casa and msa in tum

Serum mucin antigens casa and msa in tumors of the breast, ovary, lung, pancreas, bladder, colon, and prostate. A blind trial with 420 patients

✍ Peter L. Devine; Michael A. McGuckin; Louise E. Ramm; Bruce G. Ward; David Pee; 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 786 KB

Clinical features of patients who presen

Clinical features of patients who present with metastatic prostate carcinoma and serum prostate-specific antigen (PSA) levels < 10 ng/mL : The “PSA negative” patients

✍ Alison J. Birtle; Alex Freeman; John R. W. Masters; Heather A. Payne; Stephen J. 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB 👁 1 views

## Background: Although < 1% of men present with prostate-specific antigen (psa)-negative prostate carcinoma, in that they have serum psa levels much lower than the tumor burden would suggest, such patients represent a management dilemma. to the authors' knowledge, little information exists in the