Interaction of the nuclear localizing cy
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Elizabeth J. Blink; Zhou Jiansheng; Wei Hu; Sophina. T. Calanni; Joseph A. Trapa
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Article
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2005
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John Wiley and Sons
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English
โ 299 KB
Conditional on perforin-dependent delivery to the nucleus of target cells, the cytolytic granule serine protease granzyme B (GrB) plays a central role in eliciting the nuclear events of apoptosis, as shown by the fact that reducing GrB nuclear entry prevents nuclear apoptosis. Apart from a requireme