From 1976 to 1980,18 of the 250 patients (7%) seen with small cell carcinoma of the lung had clinically evident inappropriate secretion of antidiuretic hormone (ADH). Hyponatremia was usually severe (1 16 f 7 meq/l), and eight patients showed symptoms of water intoxication at the time of diagnosis.
โฆ LIBER โฆ
Ectopic atrial natriuretic peptide production in small cell lung cancer with the syndrome of inappropriate antidiuretic hormone secretion
โ Scribed by K. Shimizu; S. Nakano; Y. Nakano; M. Ando; K. Seki; N. Kameda
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 448 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0008-543X
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## Background: Tumors and tumor cell lines from two patients with small cell lung carcinoma (sclc) (one with and one without hyponatremia) were studied. ectopic production and prohormone processing of atrial natriuretic peptide (anp) were investigated to determine if a biologically active peptide w