ECTO-enzyme activity of human erythrocyte adenosine deaminase
β Scribed by Ken Bielat; George L. Tritsch
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 643 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0300-8177
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Adenosine deaminase (ADA, E.C. 3.5.4.4) is an enzyme of the purine metabolism that converts adenosine (Ado) and 2β²deoxyadenosine (dAdo) into inosine and 2β²deoxyinosine, respectively. The enzyme has been the object of considerable interest because the congenital defect causes severe combined immunode
We report a case of primary acquired slderoblastic anemia (PASA) associated with elevated erythrocyte adenosine deaminase (ADA) activity. The patient was an 85-yearold Japanese male. Analysis of the peripheral blood revealed pancytopenia, and the bone marrow findings showed marked ringed sideroblast