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Economic evaluation of prostate cancer screening with prostate-specific antigen

✍ Scribed by Tomoaki Imamura; Hideo Yasunaga


Book ID
108977691
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
68 KB
Volume
15
Category
Article
ISSN
0919-8172

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Prostate-specific antigen (PSA) is a wellcharacterized human prostate-specific glycoprotein. PSA has been shown to be the most effective immunohistologic marker for prostate cancer, as well as the most useful serologic test in staging and monitoring prostate cancer and in early detection of recurren

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## Abstract __Objective:__ To establish the value of serum prostate‐specific antigen (PSA) and prostatespecific antigen per unit volume of prostate gland (PSAD) in detecting prostate carcinoma (CaP) in a hypothetical screening algorithm, a meta‐analysis of the sensitivities, specificities, predicti

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## BACKGROUND. The 11,811 first visits and 46,751 annual follow-up visits performed since 1988 were analyzed in order to assess the efficacy of serum prostatic specific antigen (PSA) and digital rectal examination (DRE) for diagnosis of prostate cancer. METHODS. At first visit, screening included