ECHOvirus 33 replication in human peripheral white blood cells

✍ Scribed by John W. Gnann; Edward C. Hayes Jr.; Joan Z. Smith; Dr. Catherine M. Wilfert

• Publisher: John Wiley and Sons
• Year: 1979
• Tongue: English
• Weight: 529 KB
• Volume: 3
• Category: Article
• ISSN: 0146-6615
• DOI: 10.1002/jmv.1890030407

✦ Synopsis

ECHOvirus 33 isolated from the cerebrospinal fluid of a patient with agammaglobulinemia was shown to replicate in vitro in peripheral leukocyte suspensions from a normal antibody negative donor. Replication was demonstrated by use of sequential dilution experiments. Washed glass adherent mononuclear cell cultures from a normal antibody negative donor were also capable of supporting ECHOvirus 33 replication in vitro. Leukocyte suspensions from the infected agammaglobulinemic patient extinguished detectable infectious virus in vitro.