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Echo acquisition during frequency-selective pulse trains for proton spectroscopy of metabolites in vivo

✍ Scribed by Ronald A. Meyer

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 243 KB
Volume: 4
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910040311

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✦ Synopsis

Suppression of water and fat in proton spectra of rat skeletal muscle was achieved by acquisition of the spin echoes formed in the steady state after a series of frequency-selective composite pulses of constant amplitude, phase, and interpulse interval. The method enables observation of lactate in the presence of fat without resorting to difference spectroscopy, and on spectrometers which permit data acquisition immediately prior to a pulse, enables much faster data accumulation compared to standard echo sequences.

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A new approach to volume-selected in vivo NMR spectroscopy uses two frequencyshifted sinc pulses, in conjunction with pulsed field gradients, to destroy the coherence of the unwanted signals. A hard u/2 pulse can then be used to read the z magnetization in the region of interest. This method is inde