EBV-positive Burkitt's lymphoma from algeria, with a three-way rearrangement involving chromosomes 2, 8 and 9
✍ Scribed by T. Philip; G. M. Lenoir; J. Fraisse; I. Philip; J. Bertoglio; S. Ladjaj; S. Bertrand; M. Brunat-Mentigny
- Book ID
- 102278540
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- French
- Weight
- 401 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
Burkitt's lymphoma was diagnosed in a male Algerian child presenting with abdominal and jaw tumours. Viral studies revealed that this non‐endemic case was associated with the Epstein‐Barr virus. Cytogenetic examination of tumour cells showed a complex three‐way rearrangement involving chromosomes 2, 8 and 9. Our report indicates that, in Burkitt's lymphoma, not only simple but also complex translocations involving chromosome 8 may arise. This finding in a North African case emphasizes the need for more detailed study of the clinical, virological and cytogenetic features of Burkitt's lymphoma throughout the world.
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