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EBV-positive Burkitt's lymphoma from algeria, with a three-way rearrangement involving chromosomes 2, 8 and 9

✍ Scribed by T. Philip; G. M. Lenoir; J. Fraisse; I. Philip; J. Bertoglio; S. Ladjaj; S. Bertrand; M. Brunat-Mentigny


Book ID
102278540
Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
401 KB
Volume
28
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

Burkitt's lymphoma was diagnosed in a male Algerian child presenting with abdominal and jaw tumours. Viral studies revealed that this non‐endemic case was associated with the Epstein‐Barr virus. Cytogenetic examination of tumour cells showed a complex three‐way rearrangement involving chromosomes 2, 8 and 9. Our report indicates that, in Burkitt's lymphoma, not only simple but also complex translocations involving chromosome 8 may arise. This finding in a North African case emphasizes the need for more detailed study of the clinical, virological and cytogenetic features of Burkitt's lymphoma throughout the world.


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