A radioimmunoassay (RIA) has been developed and used to determine the expression of LMP-a membrane protein encoded by the LT3 region of the Epstein-Barr virus (EBV) genome-in cell lines of various origins. The RIA was highly sensitive, specific and reproducible. All EBV-negative cell lines were LMP-
EBV framed in Burkitt lymphoma
โ Scribed by Speck, Samuel H.
- Book ID
- 109931334
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 154 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1078-8956
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Latent Epstein-Barr virus (EBV) uses two alternative strategies to express the Epstein-Barr nuclear antigens (EBNAs). Resting normal B cells harboring latent virus and Burkitt's lymphoma (BL) cells use monocistronic messages generated from the Q promoter (restricted strategy). EBV-transformed immuno
Three serological reactions have been followed in a Burkitt lymphoma patient during the clinical course of the disease, including long-term regression, followed by recurrence and progressive growth, in spite ojchemotherapy. Antibodies directed against surface antigens characteristic for EB V-carryin