✦ LIBER ✦

Easy and Regioselective Synthesis of Highly Functionalized o-Quinodimethide Precursors from Fischer Carbene Complexes and Isocyanides

✍ Scribed by José Barluenga; Fernando Aznar; M. Angel Palomero

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 300 KB
Volume: 8
Category: Article
ISSN: 0947-6539
DOI: 10.1002/1521-3765(20020916)8:18<4149::aid-chem4149>3.0.co;2-r

No coin nor oath required. For personal study only.

✦ Synopsis

Highly functionalized cis- and trans-1,2-bis(trialkylsilyloxy)benzocyclobutene derivatives have been synthesized in a completely regioselective fashion from easily available Fischer alkenylcyclobutenyl(alkoxy)carbene complexes and isocyanides. This methodology can be viewed as an alternative to existing methods of synthesis of this kind of compounds and overcomes the main problem of introducing functionality in the aromatic ring. Both cis and trans derivatives underwent the expected fragmentation to generate o-quinodimethide intermediates upon thermal treatment, affording complex polycyclic structures in a stereoselective manner when heating was carried out in the presence of a range of electron deficient dienophiles.

📜 SIMILAR VOLUMES

Easy and Regioselective Synthesis of Hig

Easy and Regioselective Synthesis of Highly Functionalized o-Quinodimethide Precursors from Fischer Carbene Complexes and Isocyanides.

✍ Jose Barluenga; Fernando Aznar; M. Angel Palomero 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 245 KB

Regioselective and stereoselective synth

Regioselective and stereoselective synthesis of vinylcyclopropane derivatives from 1,3-dienes and a Fischer carbene complex

✍ Matthias Buchert; Hans-Ulrich Reissig 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 137 KB

Regioselective Synthesis of Substituted

Regioselective Synthesis of Substituted o-Alkoxyphenol Derivatives Through Thermal Benzannulation of Fischer (Alkenylcyclobutenyl)carbene Complexes.

✍ Jose Barluenga; Fernando Aznar; M. Angel Palomero 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 52 KB 👁 1 views

Efficient Synthesis of Highly Functional

Efficient Synthesis of Highly Functionalized Indazoles and 2,3-Dihydro-1,2-benzisoxazoles by Reaction of Stable Fischer Dienyl Carbenes and Isocyanides

✍ José Barluenga; Fernando Aznar; M. Angel Palomero 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 1 views

A range of stable chromium and tungsten Fischer dienyl carbenes have been prepared by [3+2] cycloaddition of alkenylethynyl carbene complexes with nitrones or diazoalkanes. Treatment of these systems with isocyanides gives entry to highly functionalized 2,3-dihydro-1,2-benzisoxazoles and indazoles i

Highly Functionalized Vinylcyclopropane

Highly Functionalized Vinylcyclopropane Derivatives by Regioselective and Stereoselective Reactions of Fischer Carbene Complexes with 1,4–Disubstituted Electron–Deficient 1,3–Dienes

✍ Buchert, Matthias ;Reißig, Hans–Ulrich 📂 Article 📅 1992 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 594 KB

A Simple Procedure for the Synthesis of

A Simple Procedure for the Synthesis of Functionalized 1,3-Butadienes and Cyclopentenones from Fischer Carbene Complexes.

✍ Francisco J. Fananas; Jorge Alonso; Felix Rodriguez 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views