We conducted a prospective, randomized, controlled trial comparing the efficacy of two doses of a reconstituted bovine surfactant (Surfactant TA) in premature infants requiring mechanical ventilation shortly after birth for respiratory distress syndrome. Forty-six infants weighting 1000-1499 g were
β¦ LIBER β¦
Early versus late surfactant replacement therapy in severe respiratory distress syndrome
β Scribed by Christian P. Speer; Karsten Harms; Egbert Herting; Norbert Neumann; Tore Curstedt; Bengt Robertson
- Book ID
- 110650717
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 365 KB
- Volume
- 168
- Category
- Article
- ISSN
- 0341-2040
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Surfactant deficiency in newborn infants with hyaline membrane disease (HMD) reduces peripheral airway stability, leading to lung atelectasis, inhomogeneity of distribution of ventilation, ventilation/perfusion mismatch, and hypoxemia. The aim of this study was to evaluate the immediate effect of ex