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Early Training May Exacerbate Brain Damage After Focal Brain Ischemia in the Rat

✍ Scribed by Risedal, Anette; Zeng, Jinsheng; Johansson, Barbro B.


Book ID
110079011
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
747 KB
Volume
19
Category
Article
ISSN
0271-678X

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## Abstract The proinflammatory cytokine interleukin‐1 (IL‐1) is a key mediator of inflammation in cerebral ischemia, but its precise mechanisms of action remain elusive. Temperature is critical to outcome in brain injury and given the importance of IL‐1 in pyrogenesis this has clear mechanistic im