๐”– Bobbio Scriptorium
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Early tissue distribution of therapeutic 131I in a patient with thyrotoxicosis

โœ Scribed by E. Vachal; A. Wegst; D. Preston; Dr. T. Tomita

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
532 KB
Volume
11
Category
Article
ISSN
0022-4790

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โœฆ Synopsis

A therapeutic dose of 13' I was given to a 53-year-old man with thyrotoxicosis three and one-half hours prior to death. The distribution of 1311 in the thyroid gland was studied by autoradiography, and the radioactivity in various fresh tissues was measured. Radioactivity was distributed evenly throughout the col-1oid;small amounts were present in follicular cells. Radioactivity was not localized to the periphery of colloid follicles as observed in an earlier report. Papillary projections were associated with increased radioactivity. Decreased ratioactivity was associated with oxyphilic cells. Measurement of ' ' ' 1 in individual tissues showed that per gram of tissue the thyroid gland contained approximately 50 times that of intestine and spleen and approximately 100 times that of liver and bone.

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