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Early Thyroid Hormone-induced Gene Expression Changes in N2a-β Neuroblastoma Cells

✍ Scribed by Gabriela Bedó; Angel Pascual; Ana Aranda


Book ID
107575340
Publisher
Humana Press Inc
Year
2010
Tongue
English
Weight
293 KB
Volume
45
Category
Article
ISSN
0895-8696

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Regulation of thyroid hormone receptor a
✍ B. Yusta; J. Ortiz-Caro; G. Bedo; A. Pascual; Ana Aranda 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 859 KB

Butyrate produced a biphasic modulation of the thyroid hormone receptor in neuroblastoma N2A cells increasing receptor number by 20-35 % at concentrations 0.25-0.75 mM and decreasing receptor levels by 3045% at 2 4 mM. The half-life of the receptor, as assessed by its disappearance after incubation