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Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

✍ Scribed by Papinski, Daniel; Schuschnig, Martina; Reiter, Wolfgang; Wilhelm, Larissa; Barnes, Christopher A.; Maiolica, Alessio; Hansmann, Isabella; Pfaffenwimmer, Thaddaeus; Kijanska, Monika; Stoffel, Ingrid; Lee, Sung Sik; Brezovich, Andrea; Lou, Jane Hua; Turk, Benjamin E.; Aebersold, Ruedi; Ammerer, Gustav; Peter, Matthias; Kraft, Claudine


Book ID
122247461
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
58 KB
Volume
53
Category
Article
ISSN
1097-2765

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Both the neuronal IIA as well as the cardiac SkM2 isoform of the pore forming alpha-subunit of voltage dependent sodium channels are modulated by Protein Kinase A. While alphaIIA becomes attenuated upon PKA stimulation, alphaSkM2 becomes upregulated. PKC dependent phosphorylation of a serine, locate