๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Early prediction of instability of chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins

โœ Scribed by Haimanti Dorai; Susanne Corisdeo; Dawn Ellis; Cherylann Kinney; Matt Chomo; Pam Hawley-Nelson; Gordon Moore; Michael J. Betenbaugh; Subinay Ganguly

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
448 KB
Volume
109
Category
Article
ISSN
0006-3592

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Mechanisms of unintended amino acid sequ
Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells
โœ Donglin Guo; Albert Gao; David A. Michels; Lauren Feeney; Marian Eng; Betty Chan ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 428 KB ๐Ÿ‘ 1 views

## Abstract An amino acid sequence variant is defined as an unintended amino acid sequence change and contributes to product heterogeneity. Recombinant monoclonal antibodies (MAbs) are primarily expressed from Chinese Hamster Ovary (CHO) cells using stably transfected production cell lines. Selecti