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Early postnatal behavioral changes in the Mecp2-308 truncation mouse model of Rett syndrome

✍ Scribed by B. De Filippis; L. Ricceri; G. Laviola


Book ID
111273328
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
663 KB
Volume
9
Category
Article
ISSN
1601-1848

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## Abstract Sandhoff's disease is a lysosomal storage disease in which the ganglioside GM2 accumulates in lysosomes. It has been reported that MRI cannot detect abnormalities in spin echo images in clinically presymptomatic Sandhoff's disease patients. Because one of the results of GM2 accumulation