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Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy

✍ Scribed by Boyer, Justin G; Murray, Lyndsay M; Scott, Kyle; De Repentigny, Yves; Renaud, Jean-Marc; Kothary, Rashmi


Book ID
121613960
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
767 KB
Volume
3
Category
Article
ISSN
2044-5040

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The expression of the genes for the ␣-subunit of AChR (AChR␣), for the myogenic factors myogenin and MyoD, for the calcium-binding protein parvalbumin (PV), and for the muscular chloride channel ClC-1 was studied in the three mouse spinal muscular atrophies (SMAs). These were the mutants ''wobbler''