Early glottic carcinoma: Treatment according patient's preference?

✍ Scribed by Sandro J. Stoeckli; Isabel Schnieper; Pia Huguenin; Stephan Schmid

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 87 KB
• Volume: 25
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.10323

✦ Synopsis

Abstract

Background.

To analyze the results in early (stage I and II) glottic carcinoma of a single institution with a patient‐oriented concept.

Methods.

After diagnostic workup and multidisciplinary counseling, either radiotherapy or CO~2~ laser surgery was chosen with respect to the patient's preference.

Results.

Sixty‐five patients underwent laser surgery and 75 had radiotherapy. For T1 tumors, the 5‐year overall survival, disease‐specific survival, and initial local control rate after laser surgery and radiotherapy were comparable (OS, 85% vs 88%; DSS, 96% vs 93%; LCR, 86% vs 85%). In contrast, initial local control for T2 tumors was significantly more favorable after surgery (OS, 83% vs 78%; DSS, 83% vs 88%; LCR, 89% vs 67%). Larynx preservation was significantly higher after surgery in T1 tumors (96% vs 82%) and in T2 tumors (89% vs 77%).

Conclusions.

Selection of the treatment modality according to patient's preference results in a comparable control of disease for T1 tumors. The initial local control for T2 tumors is significantly better after surgery. In both stages laser surgery warrants a better larynx preservation rate. © 2003 Wiley Periodicals, Inc. Head Neck 25: 000–000, 2003