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Early gene expression analyzed by cDNA microarray and RT-PCR in osteoblasts cultured with water-soluble and low molecular chitooligosaccharide

โœ Scribed by Naoko Ohara; Yoshihiko Hayashi; Shizuka Yamada; Se-Kwon Kim; Tsunenori Matsunaga; Kajiro Yanagiguchi; Takeshi Ikeda


Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
206 KB
Volume
25
Category
Article
ISSN
0142-9612

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## Abstract Chitosan has a variety of biological activities. Although it has been reported that chitosan promotes osteogenesis in bone lesions, little is known about how it modulates the hard tissue forming cells at the gene level. This study focused on gene expressions in osteoblasts cultured with