Early first-trimester maternal serum placental growth factor in trisomy 21 pregnancies
✍ Scribed by N. J. Cowans; A. Stamatopoulou; N. Tørring; K. Spencer
- Book ID
- 112230999
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 118 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0960-7692
- DOI
- 10.1002/uog.8890
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In a study of 130 ®rst trimester cases of trisomy 21 and 959 controls we have shown that the median MoM for alpha-fetoprotein (AFP) is lower (0.82) and that for total human chorionic gonadotrophin (hCG) is higher (1.31) than in the control group. For AFP 15.3% of cases were below the 5th centile and