Early effects of nucleus pulposus application on spinal nerve root morphology and function
✍ Scribed by G. Byröd; B. Rydevik; C. Nordborg; K. Olmarker
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 118 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0940-6719
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## Abstract Nerve root dysfunction and sciatic pain in disc herniation are considered to be caused by mechanical compression and related to the presence of nucleus pulposus in the epidural space. Autologous nucleus pulposus has been shown to induce endoneural edema and to decrease nerve‐conduction
Autologous nucleus pulposus is known to have injurious effects on spinal nerve roots when applied epidurally. Both inflammatory and immunological mechanisms have been implicated in this regard. Various proinflammatory substances might be released or activated by nucleus pulposus and might affect the