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Early down-regulation of cytochrome P 450 3A and 2E1 in the regenerating rat liver is not related to the loss of liver mass

✍ Scribed by P. Starkel; S. Laurent; L. Lambotte; Y. Horsmans


Book ID
119526297
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
135 KB
Volume
32
Category
Article
ISSN
0168-8278

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Cytochromes P450 (CYPs) and p-glycoproteins (Pgps) are believed to play important roles in drug absorption, metabolism, and elimination. Numerous drugs and environmental chemicals can modulate expression of these two classes of genes in different species. The present study investigated the effect of