Early Diffuse Chromosome Alterations in Monkey Kidney Cells infected in vitro with Herpes Simplex Virus

Detection of early antigens in nuclei of

Detection of early antigens in nuclei of cells infected with cytomegalovirus or herpes simplex virus type 1 and 2 by anti-complement immunofluorescence, and use of a blocking assay to demonstrate their specificity

✍ G. Giraldo; E. Beth; U. Hämmerling; G. Tarro; F. M. Kourilsky 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 French ⚖ 975 KB

## Abstract Skin fibroblasts exposed to cytosine arabinoside (Ara C) were infected with either cytomegalovirus (CMV) or herpes simplex virus (HSV) type 1 and 2. Herpesvirus‐determined early antigens (HV‐EA), detected by anti‐complement immunofluorescence (ACIF), occurred primarily in the nuclei, an