𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Early detection of regional cerebral ischemia in cats: Comparison of diffusion- and T2-weighted MRI and spectroscopy

✍ Scribed by M. E. Moseley; Y. Cohen; J. Mintorovitch; L. Chileuitt; H. Shimizu; J. Kucharczyk; M. F. Wendland; P. R. Weinstein

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
919 KB
Volume
14
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Diffusion‐weighted MR images were compared with T2‐weighted MR images and correlated with ^1^H spin‐echo and ^31^P MR Spectroscopy for 6‐8 h following a unilateral middle cerebral and bilateral carotid artery occlusion in eight cats. Diffusion‐weighted images using strong gradient strengths (b values of 1413 s/mm^2^) displayed a significant relative hyperintensity in ischemic regions as early as 45 min after onset of ischemia whereas T2‐weighted spin‐echo images failed to clearly demonstrate brain injury up to 2‐3 h postocclusion. Signal intensity ratios (SIR) of ischemic to normal tissues were greater in the diffusion‐weighted images at all times than in either TE 80 or TE 160 ms T2‐weighted MR images. Diffusion‐ and T2‐weighted SIR did not correlate for the first 1‐2 h postocclusion. Good correlation was found between diffusion‐weighted SIR and ischemic disturbances of energy metabolism as detected by ^31^P and ^1^H MR Spectroscopy. Diffusion‐weighted hyperintensity in ischemic tissues may be temperature‐related, due to rapid accumulation of diffusion‐restricted water in the intracellular space (cytotoxic edema) resulting from the breakdown of the transmembrane pump and/or to microscopic brain pulsations. © 1990 Academic Press, Inc.

📜 SIMILAR VOLUMES

Comparison of diffusion- and T2-weighted
Comparison of diffusion- and T2-weighted MRI for the early detection of cerebral ischemia and reperfusion in rats
✍ J. Mintorovitch; M. E. Moseley; L. Chileuitt; H. Shimizu; Y. Cohen; P. R. Weinst 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 764 KB

## Abstract The sensitivity of diffusion‐weighted MRI was compared to that of T2‐weighted MRI following temporary middle cerebral artery occlusion (MCA‐0) for 33 min followed by 4 h of reperfusion in rats. Diffusion‐weighted spin‐echo images using strong gradients (__b__ value of 1413 s/mm^2^) demo

Unsupervised segmentation of multiparame
Unsupervised segmentation of multiparameter MRI in experimental cerebral ischemia with comparison to T2, diffusion, and ADC MRI parameters and histopathological validation
✍ Michael A. Jacobs; Robert A. Knight; Hamid Soltanian-Zadeh; Zhang G. Zheng; Anto 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 327 KB 👁 1 views

This study presents histological validation of an objective (unsupervised) computer segmentation algorithm, the iterative self-organizing data analysis technique (ISODATA), for analysis of multiparameter magnetic resonance imaging (MRI) data in experimental focal cerebral ischemia. T2-, T1-, and dif

Prostate cancer detection with 3 T MRI:
Prostate cancer detection with 3 T MRI: Comparison of diffusion-weighted imaging and dynamic contrast-enhanced MRI in combination with T2-weighted imaging
✍ Kazuhiro Kitajima; Yasushi Kaji; Yoshitatsu Fukabori; Ken-ichiro Yoshida; Narufu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB 👁 1 views

## Abstract ## Purpose: To evaluate the diagnostic ability of diffusion‐weighted imaging (DWI) and dynamic contrast‐enhanced imaging (DCEI) in combination with T2‐weighted imaging (T2WI) for the detection of prostate cancer using 3 T magnetic resonance imaging (MRI) with a phased‐array body coil.