✦ LIBER ✦

Early detection of hepatocellular carcinoma in hepatitis-B-positive renal transplant recipients

✍ Scribed by Tang, S.; Lo, C. M.; Chan, T. M.; Lai, K. N.

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 48 KB
Volume: 72
Category: Article
ISSN: 0022-4790
DOI: 10.1002/(sici)1096-9098(199910)72:2<99::aid-jso11>3.0.co;2-1

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✦ Synopsis

Hepatocellular carcinoma (HCC) is a leading cause of malignancy after renal transplantation in Asia, where hepatitis B virus infection is endemic. Early detection and resection are the key to successful treatment because the mortality rate for HCC is high. The value of ␣-fetoprotein monitoring in the early detection of HCC in renal transplant recipients has not been reported before. We describe 2 patients who had successful resection of HCC following early diagnosis by ␣-fetoprotein monitoring. The epidemiology of post-transplant HCC in various parts of the world and its pathogenesis are discussed.

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